Pycnogenol® MARITIME PINE BARK EXTRACT (1000:1) 25mg

•  French Maritime Pine Extract - Authentic certified species Pinus pinaster Aiton.
•  Highly concentrated extract = 1000:1 ratio - 50mg is equivalent to 50g of native bark.
•  Produced exclusively with the most internationally recognised French maritime pine patent: Pycnogenol^®.
•  Standardised to 70% Procyanidins - Oligomeric flavonoids of the proanthocyanidin type.
•  Guaranteed origin: Les Landes de Gascogne - Natural forest, free from agricultural exploitation¹.

What is Pycnogenol®?

French Maritime Pine Bark Extract (1000:1) 25mg (Pycnogenol^®) from EssentialSeries is a product in vegetable capsules made from a highly concentrated extract (1000 units of native raw material per unit of resulting extract), standardised to 70% in its key active components: Procyanidins; and using the premium raw material Pycnogenol^®️.

Pycnogenol^®️ is a registered trademark of the prestigious Horphag Research laboratory, which concentrates bark extracted from the French forest Les Landes de Gascogne. Over the years, it has established itself as a reference patent in the global dietary supplement market for personal care.

French Maritime Pine Bark Extract is a must-have in your supplement routine, ideally paired with other common supplements like omega-3 or coenzyme Q10.

Discover your new favourite supplement

100% French Maritime Pine Extract

HSN's French Maritime Pine Bark Extract (1000:1) 25mg (Pycnogenol^®) is 100% pure extract with no added active ingredients, ensuring the highest concentration and effectiveness of the active compounds in maritime pine, such as its standardised procyanidins, which are flavonoids. These compounds are known for their nutritional effects, which determine their use. Being made from 100% pine extract as the only active nutrient, you can be sure that the product contains no other nutrients that may not be of interest for the effects you're seeking from Pycnogenol^®, providing an effective dose of nutrients to deliver its benefits.

Guaranteed French origin

Pycnogenol^® is a registered patent that exclusively uses French maritime pine bark extract (Pinus pinaster), grown in the forests of the Landes region, in the southwest of France.

The use of this controlled and high-quality source is why it has earned a strong global reputation in the field of dietary supplements.

Pycnogenol® Patent - The most famous on the market

Pycnogenol^® is a registered trademark of the Horphag Research laboratory, which has been in operation for over 60 years. In its Berlin-based laboratories, it developed a unique compound, a water-soluble flavonoid extracted from the bark of the French maritime pine: Pycnogenol^® French Maritime Pine Bark Extract.

HSN shares the same strong commitment to scientific research as Horphag Research, whose founder's original global vision decades ago continues to drive the company's commitment to research and development today.

25mg per capsule - The recommended dose from the manufacturer

The 25 mg dose per vegetable capsule of Pycnogenol^®, with a daily recommendation of 2 vegetable capsules, is considered ideal by Horphag Research due to the clinical studies supporting its efficacy and safety at this amount. Research conducted by the company has demonstrated that 50 mg per day (2 capsules of 25 mg) provides optimal nutritional effects. This dose has been widely tested in clinical trials. In addition, Pycnogenol^® at these amounts has sufficient bioavailability to ensure its absorption and overall action.

•  Petrassi, C., Mastromarino, A., & Spartera, C. (2000). Pycnogenol(®) in chronic venous insufficiency. Phytomedicine, 7(5), 383–388.
•  Liu, X., Wei, J., Tan, F., Zhou, S., Würthwein, G., & Rohdewald, P. (2004). Pycnogenol®, French maritime pine bark extract, improves endothelial function of hypertensive patients. Life Sciences, 74(7), 855–862.

Horphag Research also supports that this dose allows for safe long-term supplementation, which is crucial for those seeking the positive effects of French Maritime Pine Bark Extract.

Standardised to Procyanidins - Key identifiable compounds

Procyanidins are a group of phenolic compounds found in various plants, particularly in fruits, vegetables, and seeds. Chemically, procyanidins are flavanol oligomers, formed by the bonding of flavan-3-ol units such as catechin and epicatechin. These molecules assemble into chains of varying length and structure, giving them complexity in composition. The chemical structure of procyanidins influences their ability to form complexes with other substances, which is relevant to their standardisation and control in products like Pycnogenol^®, which is why it is so highly regarded.

One of the highest concentrations for an extract

A solvent-free extraction process resulting in an extract that is 1000 times more concentrated, as presented by this French maritime pine extract, is a significant advantage as it ensures a highly potent final product without degradation of its native active compounds.

By avoiding harsh solvents, the natural properties of the extract are preserved and exposure to potential residues is minimised, resulting in a superior quality dietary supplement. This high concentration also indicates an efficient and effective extraction process, allowing for greater benefits from the raw material in smaller quantities of product, which can translate into a more effective dose compared to another product with a lower extraction ratio.

Who especially uses Pycnogenol®?

•  Athletes and active individuals: Those who regularly engage in intense physical activities may find particular interest in using Pycnogenol^®, as its formulation is designed for areas of interest to those who aim to perform at their best in training.
•  Older adults: The elderly population can benefit from Pycnogenol^® due to their specific needs, for which its flavonoid composition is particularly appealing.
•  People with stressful lifestyles: Those facing high levels of stress in their daily lives may see advantages in using Pycnogenol^®, as it can be useful as a dietary supplement when leading a demanding lifestyle.

Combining Pycnogenol® with other products

The French maritime pine bark extract can be combined with any other product, as it has no known negative interactions. However, it is most commonly used alongside:

•  Coenzyme Q10 (or Ubiquinol).
•  Omega-3.
•  Turmeric Extract.
•  Garlic Extract.
•  Respi Biotics.

References

•  Iravani, S., & Zolfaghari, B. (2011). Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract. Research in Pharmaceutical Sciences, 6(1), 1–11.
•  Grether-Beck, S., Marini, A., Jaenicke, T., & Krutmann, J. (2016). French Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and Molecular Evidence. Skin Pharmacology and Physiology, 29(1), 13–17.
•  Weichmann, F., & Rohdewald, P. (2024). Pycnogenol® French maritime pine bark extract in randomized, double-blind, placebo-controlled human clinical studies. Frontiers in Nutrition, 11, 1389374.
•  Simpson, T., Kure, C., & Stough, C. (2019). Assessing the efficacy and mechanisms of Pycnogenol® on cognitive aging from in vitro animal and human studies. Frontiers in Pharmacology, 10, 694.
•  Petrassi, C., Mastromarino, A., & Spartera, C. (2000). Pycnogenol(®) in chronic venous insufficiency. Phytomedicine, 7(5), 383–388.
•  Liu, X., Wei, J., Tan, F., Zhou, S., Würthwein, G., & Rohdewald, P. (2004). Pycnogenol®, French maritime pine bark extract, improves endothelial function of hypertensive patients. Life Sciences, 74(7), 855–862.

¹ Information provided by Horphag Research via the official Pycnogenol® website - See source: Here.