- Ashwagandha Extract KSM-66® - The most concentrated ashwagandha root extract.
- KSM-66® patent: Full-spectrum extract developed after 14 years of research and refinement of the formula.
- Extracted without the use of alcoholic solvents - Following the principles of 'Green Chemistry'.
- KSM-66® is the most clinically studied ashwagandha in the world.
- Withanolides standardised to 5%. Content ensured by HPLC.
- Negligible levels of Withaferin A - Extraction with maximum quality control.
Vitaminalia presents its Ashwagandha KSM-66®
Ashwagandha KSM-66® 500mg by Vitaminalia is a food supplement in vegetable capsules made from a root extract of Withania somnifera, 12 times more concentrated, full-spectrum, standardised to 5% withanolides by HPLC, and dosed at 500mg per vegetable capsule.
Ashwagandha is one of the most renowned and valued plants in Indian Ayurveda, the traditional use of plants in many regions of the country, which has spread to all corners of the West, where extracts of these species have been studied to determine what natural elements make them so valuable. KSM-66® is the most well-known patented ashwagandha extract in the world.
Ashwagandha 500mg by Vitaminalia is one of the best options available to supplement your diet with one of the top plants in traditional Indian use.
KSM-66® - The ashwagandha extract you’re looking for
Who created KSM-66®?
Ixoreal Biomed Inc. is an Indian biotechnology company dedicated to the research and development of products based on natural ingredients, particularly when used as dietary supplements. The company has gained international recognition for its innovation in developing plant extracts, with an emphasis on the use of ashwagandha (Withania somnifera), a traditional herb of Ayurveda. Ixoreal's primary goal is to create scientifically backed products using modern methods that preserve the natural properties of plants. To this end, they have invested over 14 years in research and refinement of their products, becoming a leader in the standardisation of high-quality herbal extracts.
One of their greatest achievements is the development and patent of KSM-66®, a highly concentrated ashwagandha extract, considered the most potent on the market in terms of bioavailability and efficacy. KSM-66® is extracted using a patented 'full-spectrum extraction' process, aimed at preserving as much of the plant's natural compounds as possible, particularly the withanolides, the key bioactive compounds in ashwagandha. This extract has been the subject of numerous clinical studies, supporting the growing popularity of KSM-66®, and positioning Ixoreal Biomed as an international leader in the supplement market, especially regarding plant extracts.
Why is KSM-66® such a renowned patent?
KSM-66® is so renowned because it is one of the most concentrated and high-quality ashwagandha extracts in the world, backed by scientific studies. It stands out from other extracts due to:
- Its patented full-spectrum extraction method.
- Its standardisation of withanolides.
- Its exclusive use of the root, which is the most valued part of the plant.
- Its extraction based on green chemistry principles.

All this and more has made KSM-66® one of the best plant extracts in the supplement world.
Full-Spectrum, standardised to 5% withanolides by HPLC
The term full-spectrum in KSM-66® ashwagandha extraction refers to a method that preserves the natural composition of the plant's root in its closest form to what is found in nature. Ashwagandha root contains various bioactive compounds, including withanolides, alkaloids, saponins, and amino acids, which work together to provide the plant's properties. The full-spectrum extraction process used by KSM-66® aims to maintain a natural balance of these compounds without isolating just one, ensuring that the extract retains its natural synergy, similar to consuming the whole plant but in a more potent and bioavailable form.
The standardisation of withanolides to 5% by HPLC (High-Performance Liquid Chromatography) is valuable in the KSM-66® patent because it ensures the extract has a consistent and precise concentration of these bioactive compounds, responsible for many of the effects of ashwagandha, as reported by studies conducted with the patent. The use of HPLC guarantees the purity and quality of the extract, as it is a highly precise method that allows the exact measurement of withanolides, preventing variations in product potency.
Why KSM only uses roots for its extract
KSM-66® only uses ashwagandha root in the production of its extract because, according to Ayurvedic tradition, the root is the most valuable part of the plant, with a balanced profile of bioactive compounds, proven over centuries of use. Moreover, most scientific literature is based on the use of extracts from this part of the plant, the richest in identifying compounds like withanolides.
As Ixoreal explains on its own website, although their financial advisors have recommended using leaves as well, as they are cheaper parts of the plant, they have remained steadfast in what Indian tradition, their culture, and their corporate responsibility dictate, which is that even the name of the herb is linked to the root itself and not its aerial parts, according to Ayurvedic texts. Therefore, they only use the root.
'Green Chemistry', the principles of KSM-66®
Green Chemistry is a chemistry approach that aims to design products and processes that reduce or eliminate the use and generation of substances that may have adverse effects on the environment and human health. It is based on 12 key principles, such as using renewable raw materials, reducing waste, designing products that minimise their environmental impact at the end of their life, and using catalysts considered 100% safe compared to others with more concerns. The goal is to make industrial production more sustainable, safe, and efficient from an environmental perspective.
The fact that KSM-66® is produced based on Green Chemistry principles is positive because it ensures its production is carried out without the use of alcohol or any other chemical solvents. Moreover, its production includes the use of more efficient processes that minimise waste, use safe solvents, and reduce waste in its industrial process, contributing not only to the health of the planet but also to the safety and well-being of all users, both those who use the raw material and those who work in the plant.
Ashwagandha’s properties you don’t want to miss
Ashwagandha is characteristically an adaptogen, as it has adaptogenic properties. This essentially means:
- It improves the body’s resistance to stress.
- It promotes learning, memory, and recall.
- It helps maintain emotional stability.
- It contributes to optimal relaxation.
Thus supporting all the functions encompassed by the concept of 'adaptogen'.
Additionally, ashwagandha has other identified properties that many people seek, such as helping to maintain energy levels and feeling more energised; without stimulant alkaloids such as caffeine, for example.
500mg per capsule - High dose of high concentration
We use a dose of 500mg per vegetable capsule of ashwagandha extract, as it is considered significant, safe, and optimal according to Ixoreal, the developer of the KSM-66® raw material. 500mg per capsule has been shown to be an effective and safe dose, being at the upper end of the range that they consider ideal for achieving its full effects, as they state:
'The dose varies according to your needs, but 300 to 600mg per day for at least one month appears to be effective.'
References
- Speers, A. B., Cabey, K. A., Soumyanath, A., & Wright, K. M. (2021). Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Current Neuropharmacology, 19(9), 1468–1495.
- Gopukumar, K., Thanawala, S., Somepalli, V., Rao, T. S. S., Thamatam, V. B., & Chauhan, S. (2021). Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-Based Complementary and Alternative Medicine, 2021, 8254344.
- Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255–262.
- Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus, 11(12), e6466.