Phenylcapsaicin - Innovation and power in every capsule
Microencapsulated Phenylcapsaicin 125mg (aXivite®) from EssentialSeries is a dietary supplement in vegetable capsules made with microencapsulated phenylcapsaicin, featuring the aXivite® patent.
aXivite® is an innovative compound: Phenylcapsaicin, which is an analogue of capsaicin. Phenylcapsaicin is a patented molecule where a natural phenyl group has been used to stabilize a capsaicin identical to the natural one. Joined by a triple bond, the result is a natural capsaicin analogue, innovative, highly pure, with pungency significantly reduced (aXichem, n.d.).
HSN’s microencapsulated phenylcapsaicin is one of the most technologically advanced products currently in the supplement industry.
Harness the power of capsaicin with better tolerance
aXivite®: Microencapsulation for maximum versatility
aXivite® is a patent from aXichem, known for developing a capsaicin analogue that’s superior because it’s completely free of contaminants, with maximum purity.
Thanks to its unique microencapsulation system, the pungency—that is, the characteristic 'heat' of capsaicin—is controlled. Microencapsulated phenylcapsaicin has been developed to achieve targeted release and to enjoy a versatile version of capsaicin.
aXivite® has shown in trials conducted as part of the patent protection a very high bioavailability, generating a response superior to natural capsaicin, measured as blood concentration after intake, with the same dose. Phenylcapsaicin has positioned itself as a more efficient alternative in terms of amount-effect compared to natural capsaicin.
aXivite® has become one of the biggest innovations in the industry, and at HSN we bring it to you with the highest manufacturing guarantees, optimal doses, a practical format, and a fair price. Compare and choose right!
1% pure phenylcapsaicin, what does that mean?
Microencapsulated phenylcapsaicin aXivite® contains 1% of its content as pure phenylcapsaicin.
When we talk about 1% pure phenylcapsaicin, we mean the concentration of the active ingredient within the patented aXivite® formula. In the nutritional table, this percentage translates to the recommended daily dose of 2 capsules providing 250 mg of microencapsulated phenylcapsaicin, of which 2.5 mg correspond to pure phenylcapsaicin, the bioactive compound itself.
Each capsule contains 125 mg of aXivite®, meaning each vegetable capsule contains 1.25 mg of pure phenylcapsaicin, optimized for absorption thanks to the microencapsulation system that makes up the rest of the product content. Thanks to this novel technology, phenylcapsaicin is released more efficiently in the body, avoiding the irritating effects that other forms of capsaicin may cause, without compromising quality.
This advanced format lets you take advantage of the nutritional properties of capsaicin with greater bioavailability in a more practical way, making it an ideal option for athletes and anyone wanting to use capsaicin without digestive discomfort.
In vegetable capsules: Suitable for vegans and free from unnecessary additives
We’ve made our microencapsulated phenylcapsaicin in a vegetable capsule format, making it 100% vegan-friendly and compatible with any diet. Unlike other products that may contain animal-derived gelatin, we chose to develop our encapsulation with hydroxypropyl methylcellulose, a plant-based polymer.
Thanks to our controlled manufacturing in clean rooms, we guarantee total absence of cross-contamination with any allergens, plus a simple formulation without the need for unnecessary additives for the microencapsulation or encapsulation system, and no aesthetic ingredients.
Main properties of phenylcapsaicin
Phenylcapsaicin is an innovative capsaicin derivative designed to offer an optimized experience compared to traditional capsaicin supplementation. Thanks to its improved molecular structure and microencapsulation with the aXivite® patent, its stability and bioavailability are superior, allowing for optimal release.
This has made phenylcapsaicin a very popular choice among athletes of all levels looking for the benefits of capsaicin supplementation.
But, unlike conventional capsaicin, phenylcapsaicin was developed to provide a more tolerable profile, making it a more appealing option for many users.
What sets phenylcapsaicin apart from other forms of capsaicin?
At the molecular level, phenylcapsaicin differs from conventional capsaicin by the addition of a phenyl group in its chemical structure. This modification changes its properties, resulting in greater stability and more efficient absorption. By modifying the original capsaicin structure, phenylcapsaicin maintains its functionality while reducing some characteristic effects of the base molecule, like its high pungency. Thanks to this innovation, phenylcapsaicin has positioned itself as a compound with an optimized profile for use as a dietary supplement in athletes.
From a practical standpoint, phenylcapsaicin offers significant advantages compared to other forms of capsaicin. Its higher bioavailability allows for more efficient absorption, optimizing effects with smaller doses. Also, the microencapsulation technology in aXivite® helps improve its stability and tolerance, reducing the burning sensation usually associated with conventional capsaicin.
However, if your tolerance for spicy is good and you’re familiar with traditional capsaicin, you can use it through the product:
The science behind phenylcapsaicin: Studies and support
Phenylcapsaicin has sparked growing interest in the scientific community, leading to the publication of various trials and reviews in the field of sports nutrition and wellness. Thanks to its modified chemical structure and innovative microencapsulation technology, this compound has been studied for its bioavailability, stability, and tolerance compared to other forms of capsaicin.
Recent research has explored its potential in different applications, helping build a body of evidence around its use in advanced formulations, not only as part of blends but also as a unique compound in dietary supplement presentations like the product you’re viewing.
What to combine phenylcapsaicin with?
Phenylcapsaicin can be combined with different ingredients depending on your goals. It’s important to know there are no supplements incompatible with this compound, so you can mix it with any product.
In sports, athletes commonly use it alongside:
To create pre-workouts designed for use before exercise sessions. These combos allow for very personalized homemade stacks tailored to each athlete’s needs.
It can also be complemented with products like black pepper extract, which thanks to its piperine content, enhances phenylcapsaicin absorption.
It can also be combined with electrolytes and BCAA's if the athlete is endurance-focused.
Bibliographic references
- Jiménez-Martínez, P., Sánchez-Valdepeñas, J., Cornejo-Daza, P. J., Cano-Castillo, C., Asín-Izquierdo, I., Alix-Fages, C., … Colado, J. C. (2023). Effects of different phenylcapsaicin doses on neuromuscular activity and mechanical performance in trained male subjects: a randomized, triple-blinded, crossover, placebo-controlled trial. Frontiers in Physiology, 14, 1215644.
- Jiménez-Martínez, P., Cornejo-Daza, P. J., Sánchez-Valdepeñas, J., Asín-Izquierdo, I., Cano-Castillo, C., Alix-Fages, C., … Colado, J. C. (2023). Effects of different phenylcapsaicin doses on resistance training performance, muscle damage, protein breakdown, metabolic response, ratings of perceived exertion, and recovery: a randomized, triple-blinded, placebo-controlled, crossover trial. Journal of the International Society of Sports Nutrition, 20(1), 2204083.
- Turck, D., Castenmiller, J., De Henauw, S., Hirsch-Ernst, K. I., Kearney, J., Maciuk, A., … Knutsen, H. K. (2019). Safety of phenylcapsaicin as a novel food pursuant to Regulation (EU) 2015/2283. EFSA Journal, 17(6), e05718.
- Jiménez-Martínez, P., Alix-Fages, C., Janicijevic, D., Miras-Moreno, S., Chacón-Ventura, S., Martín-Olmedo, J. J., … Colado, J. C. (2023). Effects of phenylcapsaicin on aerobic capacity and physiological parameters in active young males: a randomized, triple-blinded, placebo-controlled, crossover trial. Frontiers in Physiology, 14, 1190345.
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